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EP ethylphenidate white powder 90% purity best quality favourable price

Hiersun Biotech Company Limited

City: zhongshan

Province/State:guangdong

Country/Region:china

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EP ethylphenidate white powder 90% purity best quality favourable price

Brand Name : Hiersun
Model Number : HS-009
Place of Origin : China
MOQ : 5g
Price : Negotiable
Payment Terms : Western Union, MoneyGram
Supply Ability : 30kg/month
Delivery Time : 1-2 days after payment
Packaging Details : aluminum foil bag
appearance : powder
color : white
CAS : 140703-51-1
email : nannie@hiersunchem.com
skype : nannie(at)hiersunchem(dot)com
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Product Detail

Model No.:140703-51-1
Production Capacity:20 Kilogram/Kilograms per D...
Delivery Date:within 3 days
CAS No.:140703-51-1
Pure:99%
Delivery time:In stock ,within 24 hours
Skype:nannie(at)hiersunchem(dot)com
Min order:10g
Means of Transport:Land, Ocean, Air
Packing:Aluminum Foil Bag
Brand Name:HS
Purity:99%
Application:lab research
Payment term:Western Union ,Money Gram, Bitcoin
Contact Email:nannie(at)hiersunchem(dot)com
Free samples:Available

1.High purity
2Guaranteed delivery
3.Multi-payment procedure
4.Reputed Supplier for over 10 years
5.Whole Range of substances for chose

Examorelin (INN) (developmental code names EP-23905, MF-6003), also known as hexarelin, is a potent,synthetic, peptidic, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue which was developed by Mediolanum Farmaceutici.[3][4][5][6][7] It is a hexapeptide with the amino acid sequence His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2 which was derived from GHRP-6. These GH-releasing peptides have no sequence similarity to ghrelin, but mimic ghrelin by acting as agonists at the ghrelin receptor.[5][6]

Examorelin substantially and dose-dependently increases plasma levels of growth hormone (GH) in animals and humans.[2] In addition, similarly to pralmorelin (GHRP-2) and GHRP-6, it slightly and dose-dependently stimulates the release of prolactin, adrenocorticotropic hormone (ACTH), and cortisol in humans.[2][8] There are conflicting reports on the ability of examorelin to elevate insulin-like growth factor 1 (IGF-1) andinsulin-like growth factor-binding protein 1 (IGFBP-1) levels in humans, with some studies finding no increase and others finding a slight yet statistically significant increase.[2][9][10][11] Examorelin does not affect plasma levels of glucose, luteinizing hormone (LH), follicle-stimulating hormone (FSH), or thyroid-stimulating hormone (TSH) in humans.[2]

Examorelin releases more GH than does growth hormone-releasing hormone (GHRH) in humans,[8][12] and produces synergistic effects on GH release in combination with GHRH, resulting in "massive" increases in plasma GH levels even with only low doses of examorelin.[13][14][15] Pre-administration of GH blunts the GH-releasing effect of examorelin, while, in contrast, fully abolishing the effect of GHRH.[14][16] Pre-treatment with IGF-1 also blunts the GH-elevating effect of examorelin.[17] Testosterone, testosterone enanthate, andethinylestradiol, though not oxandrolone, have been found to significantly potentiate the GH-releasing effects of examorelin in humans.[18][19] In accordance, likely due to increases in sex steroid levels,puberty has also been found to significantly augment the GH-elevating actions of examorelin in humans.[20]

A partial and reversible tolerance to the GH-releasing effects of examorelin occurs in humans with long-term administration (50–75% decrease in efficacy over the course of weeks to months).[21][22]

Examorelin reached phase II clinical trials for the treatment of growth hormone deficiency and congestive heart failure but did not complete development and was never marketed.

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